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How would one get type one diabetes?

(24 posts)
  1. NaMeLesS
    Member

    We have to write a paper in health class, and my topic is about a boy named Steve purposly trying to get type one, not type two, diabetes. Not my cup of tea, but I'll go with it.
    So I'm asking you if there is a way, let me rephrase that, if it is even possible to try and get type one Diabetes.

    Posted 2 years ago #
  2. There are things you can do within your lifestyle to put yourself at greater risk for developing diabetes, but you can't "make" yourself get it. That would take a pretty twisted person anyway, to want to get a horrible disease like that.

    Posted 2 years ago #
  3. James
    Member

    Most people who develop type 1 are otherwise healthy. Although the cause of type 1 diabetes is still not fully understood it is believed to be of immunological origin. There is a growing body of evidence that diet may play a role in the development of type 1 diabetes, through influencing gut flora, intestinal permeability, and immune function in the gut; wheat in particular has been shown to have a connection to the development of type 1 diabetes, although the relationship is poorly understood.

    Posted 2 years ago #
  4. Jeremy D
    Member

    Type 1 diabetes is a histocompatibility immunological disorder thought to be caused by beta cells of the pancreas present improper antigens to T cells. According to wikipedia the primary gene though to influence the poly-genetic trait that leads to type 1 diabetes is a macro histocompatibility complex (MHC II) gene in chromosome 6.

    I'm not going to go through the process of antigen presentation to helper T cells and the activation of an immune response through the production of interleukin, however it is an important topic which you may want to familiarize yourself. An important consequence of this process is that if any point your body begins the process of antibody production for an antigen associated with the pancreases' beta cells, essentially type 1 diabetes could develop.

    What are some scenarios in which one could induce such a response? Well the more likely one is that Steve gets a pancreas transplant. Since MHCs come in such a large variety in the human population, getting organs from other people will likely lead to a severe immune response, and eventual organ rejection. This is countered by immune-suppressants, taken throughout an organ recipients lifetime, and thus failure to take such medications could lead to failure of the pancreas and eventually lack of insulin production, characterized by type 1 diabetes.

    Another scenario is that Steve takes a radioactive isotope, such as uranium, carves it into a knife and stabs his pancreas until cancer develops. (another source of radiation, or other carcinogenic substance could substitute this process).

    Good luck on your paper. I hope this is enough to at least get your started.

    Posted 2 years ago #
  5. Stephen
    Member

    its genetic so you can't "get" it or not

    Posted 2 years ago #
  6. Stephen
    Member

    its genetic so you can't "get" it or not

    Posted 2 years ago #
  7. Stephen
    Member

    its genetic so you can't "get" it or not

    Posted 2 years ago #
  8. Stephen
    Member

    its genetic so you can't "get" it or not

    Posted 2 years ago #
  9. Stephen
    Member

    its genetic so you can't "get" it or not

    Posted 2 years ago #
  10. Stephen
    Member

    its genetic so you can't "get" it or not

    Posted 2 years ago #
  11. Stephen
    Member

    its genetic so you can't "get" it or not

    Posted 2 years ago #
  12. Stephen
    Member

    its genetic so you can't "get" it or not

    Posted 2 years ago #
  13. Stephen
    Member

    its genetic so you can't "get" it or not

    Posted 2 years ago #
  14. Stephen
    Member

    its genetic so you can't "get" it or not

    Posted 2 years ago #
  15. Stephen
    Member

    its genetic so you can't "get" it or not

    Posted 2 years ago #
  16. Stephen
    Member

    its genetic so you can't "get" it or not

    Posted 2 years ago #
  17. Stephen
    Member

    its genetic so you can't "get" it or not

    Posted 2 years ago #
  18. Stephen
    Member

    its genetic so you can't "get" it or not

    Posted 2 years ago #
  19. Stephen
    Member

    its genetic so you can't "get" it or not

    Posted 2 years ago #
  20. Stephen
    Member

    its genetic so you can't "get" it or not

    Posted 2 years ago #
  21. Stephen
    Member

    its genetic so you can't "get" it or not

    Posted 2 years ago #
  22. Stephen
    Member

    its genetic so you can't "get" it or not

    Posted 2 years ago #
  23. Stephen
    Member

    its genetic so you can't "get" it or not

    Posted 2 years ago #
  24. Stephen
    Member

    its genetic so you can't "get" it or not

    Posted 2 years ago #

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